Randomised controlled trial of tailored support to increase physical activity and reduce smoking in smokers not immediately ready to quit: protocol for the Trial of physical Activity-assisted Reduction of Smoking (TARS) Study

physical activity
RCT
smoking cessation
Authors

Taylor, Adrian

Thompson, Tom P.

Ussher, Michael

Aveyard, Paul

Murray, Rachael L.

Harris, Tess

Creanor, Siobhan

Green, Colin

Streeter, Adam Justin

Chynoweth, Jade

Ingram, Wendy

Greaves, Colin J.

Hancocks, Helen

Snowsill, Tristan

Callaghan, Lynne

Price, Lisa

Horrell, Jane

King, Jennie

Gude, Alex

George, Mary

Wahlich, Charlotte

Hamilton, Louisa

Cheema, Kelisha

Campbell, Sarah

Preece, Dan

Published

Dec 2020

Abstract

Introduction Smoking reduction can lead to increased success in quitting. This study aims to determine if a client-focused motivational support package for smoking reduction (and quitting) and increasing (or otherwise using) physical activity (PA) can help smokers who do not wish to quit immediately to reduce the amount they smoke, and ultimately quit. This paper reports the study design and methods.Methods and analysis A pragmatic, multicentred, parallel, two group, randomised controlled superiority clinical trial, with embedded process evaluation and economics evaluation. Participants who wished to reduce smoking with no immediate plans to quit were randomised 1:1 to receive either (1) tailored individual health trainer face-to-face and/or telephone support to reduce smoking and increase PA as an aid to smoking reduction (intervention) or (2) brief written/electronic advice to reduce or quit smoking (control). Participants in both arms of the trial were also signposted to usual local support for smoking reduction and quitting. The primary outcome measure is 6-month carbon monoxide-confirmed floating prolonged abstinence following participant self-reported quitting on a mailed questionnaire at 3 and 9-months post-baseline. Participants confirmed as abstinent at 9 months will be followed up at 15 months.Ethics and dissemination Approved by SW Bristol National Health Service Research Committee (17/SW/0223). Dissemination will include publication of findings for the stated outcomes, parallel process evaluation and economic evaluation in peer-reviewed journals. Results will be disseminated to trial participants and healthcare providers. Trial registration number ISRCTN47776579; Pre-results.

Citation

BibTeX citation:
@article{adrian2020,
  author = {Taylor, Adrian and Thompson, Tom P. and Ussher, Michael and
    Aveyard, Paul and Murray, Rachael L. and Harris, Tess and Creanor,
    Siobhan and Green, Colin and Streeter, Adam Justin and Chynoweth,
    Jade and Ingram, Wendy and Greaves, Colin J. and Hancocks, Helen and
    Snowsill, Tristan and Callaghan, Lynne and Price, Lisa and Horrell,
    Jane and King, Jennie and Gude, Alex and George, Mary and Wahlich,
    Charlotte and Hamilton, Louisa and Cheema, Kelisha and Campbell,
    Sarah and Preece, Dan},
  title = {Randomised Controlled Trial of Tailored Support to Increase
    Physical Activity and Reduce Smoking in Smokers Not Immediately
    Ready to Quit: Protocol for the {Trial} of Physical
    {Activity-assisted} {Reduction} of {Smoking} {(TARS)} {Study}},
  journal = {BMJ Open},
  volume = {10},
  number = {12},
  pages = {e043331},
  date = {2020-12-01},
  url = {https://tristansnowsill.co.uk/randomised-controlled-trial-of-tailored-support.html},
  doi = {10.1136/bmjopen-2020-043331},
  langid = {en},
  abstract = {Introduction Smoking reduction can lead to increased
    success in quitting. This study aims to determine if a
    client-focused motivational support package for smoking reduction
    (and quitting) and increasing (or otherwise using) physical activity
    (PA) can help smokers who do not wish to quit immediately to reduce
    the amount they smoke, and ultimately quit. This paper reports the
    study design and methods.Methods and analysis A pragmatic,
    multicentred, parallel, two group, randomised controlled superiority
    clinical trial, with embedded process evaluation and economics
    evaluation. Participants who wished to reduce smoking with no
    immediate plans to quit were randomised 1:1 to receive either (1)
    tailored individual health trainer face-to-face and/or telephone
    support to reduce smoking and increase PA as an aid to smoking
    reduction (intervention) or (2) brief written/electronic advice to
    reduce or quit smoking (control). Participants in both arms of the
    trial were also signposted to usual local support for smoking
    reduction and quitting. The primary outcome measure is 6-month
    carbon monoxide-confirmed floating prolonged abstinence following
    participant self-reported quitting on a mailed questionnaire at 3
    and 9-months post-baseline. Participants confirmed as abstinent at 9
    months will be followed up at 15 months.Ethics and dissemination
    Approved by SW Bristol National Health Service Research Committee
    (17/SW/0223). Dissemination will include publication of findings for
    the stated outcomes, parallel process evaluation and economic
    evaluation in peer-reviewed journals. Results will be disseminated
    to trial participants and healthcare providers. Trial registration
    number ISRCTN47776579; Pre-results.}
}
For attribution, please cite this work as:
Taylor, Adrian, Thompson, Tom P., Ussher, Michael, Aveyard, Paul, Murray, Rachael L., Harris, Tess, Creanor, Siobhan, et al. 2020. “Randomised Controlled Trial of Tailored Support to Increase Physical Activity and Reduce Smoking in Smokers Not Immediately Ready to Quit: Protocol for the Trial of Physical Activity-Assisted Reduction of Smoking (TARS) Study.” BMJ Open 10 (12): e043331. https://doi.org/10.1136/bmjopen-2020-043331.